Prozac and similar drugs are "little better than placebos" according to a new review. The analysis, published February 26, 2008 in the journal, Public Library of Science Medicine, looked at data from over 47 clinical trials, including data that the manufacturers chose not to publish. The trials compared the effects of the drugs versus a placebo. An analysis of the data showed that patients taking the medications (which included Prozac, Effexor, and Serzone), showed improvement, but those taking the placebo improved just as much. The only exception, the most severely depressed patients did better on the drugs.
Although patients with severe depression need pharmaceutical treatment, patients with mild to moderate depression would do much better with a mix of exercise, dietary changes, and cognitive therapy.
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