Thursday, July 10, 2008

Do You Feel Life is Worth Living?

In Japanese, the phrase ikigai translates to "life worth living". In a Japanese study, researchers looked at how a belief that life is worth living affects mortality. 43,391 Japanese adults were asked the question "Do you have ikigai in your life?". Among the subjects who died over the next seven years, a significantly higher number of them expressed that they did not have a sense that life was worth living. These people also had a higher risk for cardiovascular disease and other external causes of mortality.

Personality as a Longevity Predictor

In a study to determine the effects of personality on longevity, the personality traits of 2359 people aged 17-98 were assessed. Over the course of the study 40% of participants passed away. Those who were found to be more extroverted, emotionally stable, or conscientious lived on average 2 to 3 years longer than those who scored below the mean in those areas. These results are independent from the effects of smoking, obesity, or gender differences. Specifically, emotional stability proved to be a strong predictor for deaths from cardiovascular disease.

Supplementing for Mild Depression

For relief from mild depression, Dr. Andrew Weil suggests adding vitamins, minerals, and antioxidant rich supplements to a well-balanced diet. Dr. Weil recommends four specific supplements: B vitamins, St. Johns Wort, SAMe(S-adenosylmethionine), and fish oil. Research has shown that patients with depression have exhibited lower levels of B vitamins, specifically B6. B6 is found in many different foods such as salmon and peanut butter, but can also be found in pill form. St. Johns Wort has also yielded promising results as an alternative treatment for depression. In studies, standardized extracts of St. Johns Wort have proven as effective as Prozac at treating depression, although it should not be combined with birth control, anti-retroviral medications, or antidepressant medications. SAMe had similar results to St. Johns Wort but has been shown to work more quickly. The omega-3 fatty acids in fish oil are helpful in promoting overall positive feelings. 1000-2000 mg per day of fish oil can be useful in treating mild forms of depression according to Dr. Weil.

Friday, June 20, 2008

Depression associated with decreased Vitamin D levels in older adults

In a large population-based cohort study from Amsterdam involving 1282 older adults between the ages of 65 and 95, vitamin D status was found to be compromised in patients with minor or major depressive disorders. Additional research is needed to assess the effects of vitamin D supplementation on depression incidence in this population.

Potential new role for red grape seeds in treatment of Alzheimer's Disease

Researchers at the Mount Sinai School of Medicine have discovered that polyphenolics derived from red grape seeds may be useful agents to prevent or treat Alzheimer's disease. They tested the hypothesis that certain molecules contained in red wine, in particular in red grape seeds, might offset disease progression in mice. They are currently investigating nearly 5000 compounds found in red wine.

Sunday, May 18, 2008

Omega-3 EPA linked with reduced levels of depression

Increased blood levels of the omega-3 fatty acid, EPA, may reduce the severity of symptoms of depression, particularly in people taking antidepressants, suggests new research from France. In a study of 1390 subjects, EPA levels in people with depression were approximately .16% lower than in those without depression. What is interesting is that the subjects in the study group were taking antidepressants. These results add to the growing body of evidence linking omega-3 insufficiency with mental disorders.

Friday, April 25, 2008

Portable Biofeedback Devices Can Significantly Reduce Anxiety

In a study published in Applied Psychophysiology and Biofeedback, March, 2008, participants using a portable Respiratory Sinus Arrhythmia (RSA) biofeedback trainer reported a significant reduction in anxiety, anger and sleep disturbances. They found the device more helpful than other relaxation techniques, such as meditation, yoga, and unassisted breathing techniques.

These devices guide the participant to synchronize slow, controlled breathing with heart rate. Many of my patients have reported benefits from using the Emwave or the Stress Eraser.